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An FHA domain–mediated protein interaction network of Rad53 reveals its role in polarized cell growth

The DNA damage checkpoint kinase Rad53 is important for the survival of budding yeast under genotoxic stresses. We performed a biochemical screen to identify proteins with specific affinity for the two Forkhead associated (FHA) domains of Rad53. The N-terminal FHA1 domain was found to coordinate a c...

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Detalles Bibliográficos
Autores principales: Smolka, Marcus B., Chen, Sheng-hong, Maddox, Paul S., Enserink, Jorrit M., Albuquerque, Claudio P., Wei, Xiao X., Desai, Arshad, Kolodner, Richard D., Zhou, Huilin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064674/
https://www.ncbi.nlm.nih.gov/pubmed/17130285
http://dx.doi.org/10.1083/jcb.200605081