Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery

Inactivation of eukaryotic 2-Cys peroxiredoxins (Prxs) by hyperoxidation has been proposed to promote accumulation of hydrogen peroxide (H(2)O(2)) for redox-dependent signaling events. We examined the oxidation and oligomeric states of PrxI and -II in epithelial cells during mitogenic signaling and...

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Detalles Bibliográficos
Autores principales: Phalen, Timothy J., Weirather, Kelly, Deming, Paula B., Anathy, Vikas, Howe, Alan K., van der Vliet, Albert, Jönsson, Thomas J., Poole, Leslie B., Heintz, Nicholas H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064677/
https://www.ncbi.nlm.nih.gov/pubmed/17145963
http://dx.doi.org/10.1083/jcb.200606005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064677/
https://www.ncbi.nlm.nih.gov/pubmed/17145963
http://dx.doi.org/10.1083/jcb.200606005

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