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Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site

Eukaryotic cells have a surveillance mechanism that identifies aberrantly processed pre-mRNAs and prevents their flow to the cytoplasm by tethering them near the site of transcription. Here we provide evidence that mRNA release from the transcription site requires the heptad repeat structure of the...

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Detalles Bibliográficos
Autores principales: Custódio, Noélia, Vivo, Maria, Antoniou, Michael, Carmo-Fonseca, Maria
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064756/
https://www.ncbi.nlm.nih.gov/pubmed/17938247
http://dx.doi.org/10.1083/jcb.200612109