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Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptor

Actin assembly at the leading edge of migrating cells depends on the availability of high-affinity free barbed ends (FBE) that drive actin filament elongation and subsequent membrane protrusion. We investigated the specific mechanisms through which the Rac1 and Rac2 small guanosine triphosphatases (...

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Detalles Bibliográficos
Autores principales: Sun, Chun Xiang, Magalhães, Marco A.O., Glogauer, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064760/
https://www.ncbi.nlm.nih.gov/pubmed/17954607
http://dx.doi.org/10.1083/jcb.200705122