Cargando…

Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptor

Actin assembly at the leading edge of migrating cells depends on the availability of high-affinity free barbed ends (FBE) that drive actin filament elongation and subsequent membrane protrusion. We investigated the specific mechanisms through which the Rac1 and Rac2 small guanosine triphosphatases (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Chun Xiang, Magalhães, Marco A.O., Glogauer, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064760/ https://www.ncbi.nlm.nih.gov/pubmed/17954607 http://dx.doi.org/10.1083/jcb.200705122

Ejemplares similares

Clathrin-mediated endocytosis regulates fMLP-mediated neutrophil polarization
por: Tan, Xinyu, et al.
Publicado: (2018)

fMLP-Induced IL-8 Release Is Dependent on NADPH Oxidase in Human Neutrophils
por: Hidalgo, María A., et al.
Publicado: (2015)

Prolyl-Isomerase Pin1 Controls Key fMLP-Induced Neutrophil Functions
por: Bedouhene, Samia, et al.
Publicado: (2021)

THERAPEUTIC ASSESSMENT OF N-FORMYL-METHIONYL-LEUCYL-PHENYLALANINE (fMLP) IN REDUCING PERIPROSTHETIC JOINT INFECTION
por: Hamilton, J.L., et al.
Publicado: (2021)

Scant Extracellular NAD Cleaving Activity of Human Neutrophils is Down-Regulated by fMLP via FPRL1
por: Hasan, Md. Ashraful, et al.
Publicado: (2014)

Regulation of leading edge microtubule and actin dynamics downstream of Rac1
por: Wittmann, Torsten, et al.
Publicado: (2003)

Gram-Negative Bacteria Salmonella typhimurium Boost Leukotriene Synthesis Induced by Chemoattractant fMLP to Stimulate Neutrophil Swarming
por: Golenkina, Ekaterina A., et al.
Publicado: (2022)

Exhaustive Exercise Increases Spontaneous but Not fMLP-Induced Production of Reactive Oxygen Species by Circulating Phagocytes in Amateur Sportsmen
por: Chmielecki, Adam, et al.
Publicado: (2022)

Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1
por: Grikscheit, Katharina, et al.
Publicado: (2015)

Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin
por: Galkina, Svetlana I., et al.
Publicado: (2017)

Polymorphonuclear Cell Chemotaxis and Suicidal NETosis: Simultaneous Observation Using fMLP, PMA, H7, and Live Cell Imaging
por: Pai, Delou, et al.
Publicado: (2020)

Serum of limb remote ischemic postconditioning inhibits fMLP-triggered activation and reactive oxygen species releasing of rat neutrophils
por: Chen, Gangling, et al.
Publicado: (2021)

Essential role of protein kinase C ζ in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP
por: Kuribayashi, Kageaki, et al.
Publicado: (2007)

Erratum to “Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin”
por: Galkina, Svetlana I., et al.
Publicado: (2018)

The evolutionary history of effectors downstream of Cdc42 and Rac
por: Cotteret, Sophie, et al.
Publicado: (2002)

LRRK2 is involved in the chemotaxis of neutrophils and differentiated HL-60 cells, and the inhibition of LRRK2 kinase activity increases fMLP-induced chemotactic activity
por: Mazaki, Yuichi, et al.
Publicado: (2023)

Treponema denticola Major Outer Sheath Protein Induces Actin Assembly at Free Barbed Ends by a PIP2-Dependent Uncapping Mechanism in Fibroblasts
por: Visser, Michelle B., et al.
Publicado: (2011)

Serine-71 Phosphorylation of Rac1 Modulates Downstream Signaling
por: Schwarz, Janett, et al.
Publicado: (2012)

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding
por: Frantz, Christian, et al.
Publicado: (2008)

The dynamic instability of actin filament barbed ends
por: Romet-Lemonne, Guillaume, et al.
Publicado: (2021)

A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association
por: Seyama, Rie, et al.
Publicado: (2023)

RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling
por: Zhu, Haixia, et al.
Publicado: (2023)

Spatio-Temporal Regulation of Rac1 Mobility by Actin Islands
por: Lakhani, Vinal V., et al.
Publicado: (2015)

Rac1 is a downstream effector of PKCα in structural synaptic plasticity
por: Tu, Xun, et al.
Publicado: (2020)

Rac1 Deletion Causes Thymic Atrophy
por: Hunziker, Lukas, et al.
Publicado: (2011)

Processive acceleration of actin barbed-end assembly by N-WASP
por: Khanduja, Nimisha, et al.
Publicado: (2014)

Activating Rac
por: Tuma, Rabiya S.
Publicado: (2006)

Interplay of PKA and Rac: Fine-tuning of Rac localization and signaling
por: Bachmann, Verena A, et al.
Publicado: (2013)

Rac‐GTPases and Rac‐GEFs in neutrophil adhesion, migration and recruitment
por: Pantarelli, Chiara, et al.
Publicado: (2018)

Rac-GEF/Rac Signaling and Metastatic Dissemination in Lung Cancer
por: Cooke, Mariana, et al.
Publicado: (2020)

Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis
por: D’Ambrosi, Nadia, et al.
Publicado: (2014)

Integration of the Rac1- and actin-binding properties of Coronin-1C
por: Tilley, Frances C, et al.
Publicado: (2015)

Regulating Rac in the Nervous System: Molecular Function and Disease Implication of Rac GEFs and GAPs
por: Bai, Yanyang, et al.
Publicado: (2015)

Physiological Function of Rac Prophage During Biofilm Formation and Regulation of Rac Excision in Escherichia coli K-12
por: Liu, Xiaoxiao, et al.
Publicado: (2015)

VASP is a processive actin polymerase that requires monomeric actin for barbed end association
por: Hansen, Scott D., et al.
Publicado: (2010)

LRRK2 decreases microglial actin dynamics by filamentous actin depolymerization and Rac1 inhibition
por: Kim, Beomsue, et al.
Publicado: (2022)

Correction: Rac1 Deletion Causes Thymic Atrophy
por: Hunziker, Lukas, et al.
Publicado: (2011)

RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1
por: Meyer zum Büschenfelde, Uta, et al.
Publicado: (2018)

An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin–polymerizing machine
por: Scita, Giorgio, et al.
Publicado: (2001)

Dynamics of ligand-induced, Rac1-dependent anchoring of cadherins to the actin cytoskeleton
por: Lambert, Mireille, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_malbit0bc89dln4vh4a9c484g4