Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres

Organ homeostasis and organismal survival are related to the ability of stem cells to sustain tissue regeneration. As a consequence of accelerated telomerase shortening, telomerase-deficient mice show defective tissue regeneration and premature death. This suggests a direct impact of telomere length...

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Detalles Bibliográficos
Autores principales: Siegl-Cachedenier, Irene, Flores, Ignacio, Klatt, Peter, Blasco, Maria A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064764/
https://www.ncbi.nlm.nih.gov/pubmed/17954610
http://dx.doi.org/10.1083/jcb.200704141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064764/
https://www.ncbi.nlm.nih.gov/pubmed/17954610
http://dx.doi.org/10.1083/jcb.200704141

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