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Hif-1α regulates differentiation of limb bud mesenchyme and joint development

Recent evidence suggests that low oxygen tension (hypoxia) may control fetal development and differentiation. A crucial mediator of the adaptive response of cells to hypoxia is the transcription factor Hif-1α. In this study, we provide evidence that mesenchymal condensations that give origin to endo...

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Detalles Bibliográficos
Autores principales: Provot, Sylvain, Zinyk, Dawn, Gunes, Yasemin, Kathri, Richa, Le, Quynh, Kronenberg, Henry M., Johnson, Randall S., Longaker, Michael T., Giaccia, Amato J., Schipani, Ernestina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064828/
https://www.ncbi.nlm.nih.gov/pubmed/17470636
http://dx.doi.org/10.1083/jcb.200612023