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Hif-1α regulates differentiation of limb bud mesenchyme and joint development
Recent evidence suggests that low oxygen tension (hypoxia) may control fetal development and differentiation. A crucial mediator of the adaptive response of cells to hypoxia is the transcription factor Hif-1α. In this study, we provide evidence that mesenchymal condensations that give origin to endo...
Autores principales: | Provot, Sylvain, Zinyk, Dawn, Gunes, Yasemin, Kathri, Richa, Le, Quynh, Kronenberg, Henry M., Johnson, Randall S., Longaker, Michael T., Giaccia, Amato J., Schipani, Ernestina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064828/ https://www.ncbi.nlm.nih.gov/pubmed/17470636 http://dx.doi.org/10.1083/jcb.200612023 |
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