Cargando…

Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell–cell adhesion

Spatiotemporal coordination of cell–cell adhesion involving lamellipodial interactions, cadherin engagement, and the lateral expansion of the contact is poorly understood. Using high-resolution live-cell imaging, biosensors, and small molecule inhibitors, we investigate how Rac1 and RhoA regulate ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamada, Soichiro, Nelson, W. James
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064836/
https://www.ncbi.nlm.nih.gov/pubmed/17646397
http://dx.doi.org/10.1083/jcb.200701058