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Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell–cell adhesion
Spatiotemporal coordination of cell–cell adhesion involving lamellipodial interactions, cadherin engagement, and the lateral expansion of the contact is poorly understood. Using high-resolution live-cell imaging, biosensors, and small molecule inhibitors, we investigate how Rac1 and RhoA regulate ac...
Autores principales: | Yamada, Soichiro, Nelson, W. James |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064836/ https://www.ncbi.nlm.nih.gov/pubmed/17646397 http://dx.doi.org/10.1083/jcb.200701058 |
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