uPAR induces epithelial–mesenchymal transition in hypoxic breast cancer cells

Hypoxia activates genetic programs that facilitate cell survival; however, in cancer, it may promote invasion and metastasis. In this study, we show that breast cancer cells cultured in 1.0% O(2) demonstrate changes consistent with epithelial–mesenchymal transition (EMT). Snail translocates to the n...

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Detalles Bibliográficos
Autores principales: Lester, Robin D., Jo, Minji, Montel, Valérie, Takimoto, Shinako, Gonias, Steven L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064849/
https://www.ncbi.nlm.nih.gov/pubmed/17664334
http://dx.doi.org/10.1083/jcb.200701092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064849/
https://www.ncbi.nlm.nih.gov/pubmed/17664334
http://dx.doi.org/10.1083/jcb.200701092

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