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Both TRIM5α and TRIMCyp have only weak antiviral activity in canine D17 cells

BACKGROUND: TRIM5α, which is expressed in most primates and the related TRIMCyp, which has been found in one of the New World monkey species, are antiviral proteins of the TRIM5 family that are able to intercept incoming retroviruses early after their entry into cells. The mechanism of action has be...

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Detalles Bibliográficos
Autores principales: Bérubé, Julie, Bouchard, Amélie, Berthoux, Lionel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064933/
https://www.ncbi.nlm.nih.gov/pubmed/17892575
http://dx.doi.org/10.1186/1742-4690-4-68