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Inhibition of Protein Aggregation: Supramolecular Assemblies of Arginine Hold the Key

BACKGROUND: Aggregation of unfolded proteins occurs mainly through the exposed hydrophobic surfaces. Any mechanism of inhibition of this aggregation should explain the prevention of these hydrophobic interactions. Though arginine is prevalently used as an aggregation suppressor, its mechanism of act...

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Detalles Bibliográficos
Autores principales: Das, Utpal, Hariprasad, Gururao, Ethayathulla, Abdul S., Manral, Pallavi, Das, Taposh K., Pasha, Santosh, Mann, Anita, Ganguli, Munia, Verma, Amit K., Bhat, Rajiv, Chandrayan, Sanjeev Kumar, Ahmed, Shubbir, Sharma, Sujata, Kaur, Punit, Singh, Tej P., Srinivasan, Alagiri
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064962/
https://www.ncbi.nlm.nih.gov/pubmed/18000547
http://dx.doi.org/10.1371/journal.pone.0001176