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Inhibition of Protein Aggregation: Supramolecular Assemblies of Arginine Hold the Key
BACKGROUND: Aggregation of unfolded proteins occurs mainly through the exposed hydrophobic surfaces. Any mechanism of inhibition of this aggregation should explain the prevention of these hydrophobic interactions. Though arginine is prevalently used as an aggregation suppressor, its mechanism of act...
Autores principales: | Das, Utpal, Hariprasad, Gururao, Ethayathulla, Abdul S., Manral, Pallavi, Das, Taposh K., Pasha, Santosh, Mann, Anita, Ganguli, Munia, Verma, Amit K., Bhat, Rajiv, Chandrayan, Sanjeev Kumar, Ahmed, Shubbir, Sharma, Sujata, Kaur, Punit, Singh, Tej P., Srinivasan, Alagiri |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064962/ https://www.ncbi.nlm.nih.gov/pubmed/18000547 http://dx.doi.org/10.1371/journal.pone.0001176 |
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