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Self-Assembly and DNA Binding of the Blocking Factor in X Chromosome Inactivation
X chromosome inactivation (XCI) is the phenomenon occurring in female mammals whereby dosage compensation of X-linked genes is obtained by transcriptional silencing of one of their two X chromosomes, randomly chosen during early embryo development. The earliest steps of random X-inactivation, involv...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2065890/ https://www.ncbi.nlm.nih.gov/pubmed/17997592 http://dx.doi.org/10.1371/journal.pcbi.0030210 |