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MORPH: Probabilistic Alignment Combined with Hidden Markov Models of cis-Regulatory Modules

The discovery and analysis of cis-regulatory modules (CRMs) in metazoan genomes is crucial for understanding the transcriptional control of development and many other biological processes. Cross-species sequence comparison holds much promise for improving computational prediction of CRMs, for elucid...

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Detalles Bibliográficos
Autores principales: Sinha, Saurabh, He, Xin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2065892/
https://www.ncbi.nlm.nih.gov/pubmed/17997594
http://dx.doi.org/10.1371/journal.pcbi.0030216