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MORPH: Probabilistic Alignment Combined with Hidden Markov Models of cis-Regulatory Modules
The discovery and analysis of cis-regulatory modules (CRMs) in metazoan genomes is crucial for understanding the transcriptional control of development and many other biological processes. Cross-species sequence comparison holds much promise for improving computational prediction of CRMs, for elucid...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2065892/ https://www.ncbi.nlm.nih.gov/pubmed/17997594 http://dx.doi.org/10.1371/journal.pcbi.0030216 |