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Homozygosity by descent mapping of blood pressure in the Old Order Amish: evidence for sex specific genetic architecture

BACKGROUND: High blood pressure is a well established risk factor for morbidity and mortality acting through heart disease, stroke and cardiovascular disease. Genome wide scans have linked regions of nearly every human chromosome to blood pressure related traits. We have capitalized on beneficial qu...

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Detalles Bibliográficos
Autores principales: McArdle, Patrick F, Dytch, Harvey, O'Connell, Jeffery R, Shuldiner, Alan R, Mitchell, Braxton D, Abney, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071912/
https://www.ncbi.nlm.nih.gov/pubmed/17908314
http://dx.doi.org/10.1186/1471-2156-8-66