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The isothiocyanate class of bioactive nutrients covalently inhibit the MEKK1 protein kinase

BACKGROUND: Dietary isothiocyanates (ITCs) are electrophilic compounds that have diverse biological activities including induction of apoptosis and effects on cell cycle. They protect against experimental carcinogenesis in animals, an activity believed to result from the transcriptional induction of...

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Detalles Bibliográficos
Autores principales: Cross, Janet V, Foss, Frank W, Rady, Joshua M, Macdonald, Timothy L, Templeton, Dennis J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071920/
https://www.ncbi.nlm.nih.gov/pubmed/17894894
http://dx.doi.org/10.1186/1471-2407-7-183