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Nanosize Titanium Dioxide Stimulates Reactive Oxygen Species in Brain Microglia and Damages Neurons in Vitro

BACKGROUND: Titanium dioxide is a widely used nanomaterial whose photo-reactivity suggests that it could damage biological targets (e.g., brain) through oxidative stress (OS). OBJECTIVES: Brain cultures of immortalized mouse microglia (BV2), rat dopaminergic (DA) neurons (N27), and primary cultures...

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Detalles Bibliográficos
Autores principales: Long, Thomas C., Tajuba, Julianne, Sama, Preethi, Saleh, Navid, Swartz, Carol, Parker, Joel, Hester, Susan, Lowry, Gregory V., Veronesi, Bellina
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072833/
https://www.ncbi.nlm.nih.gov/pubmed/18007996
http://dx.doi.org/10.1289/ehp.10216