PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice

BACKGROUND: Deficiency of the PERK eIF2α kinase in humans and mice results in postnatal exocrine pancreatic atrophy as well as severe growth and metabolic anomalies in other organs and tissues. To determine if the exocrine pancreatic atrophy is due to a cell-autonomous defect, the Perk gene was spec...

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Detalles Bibliográficos
Autores principales: Iida, Kaori, Li, Yulin, McGrath, Barbara C, Frank, Ami, Cavener, Douglas R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072952/
https://www.ncbi.nlm.nih.gov/pubmed/17727724
http://dx.doi.org/10.1186/1471-2121-8-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072952/
https://www.ncbi.nlm.nih.gov/pubmed/17727724
http://dx.doi.org/10.1186/1471-2121-8-38

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