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PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice
BACKGROUND: Deficiency of the PERK eIF2α kinase in humans and mice results in postnatal exocrine pancreatic atrophy as well as severe growth and metabolic anomalies in other organs and tissues. To determine if the exocrine pancreatic atrophy is due to a cell-autonomous defect, the Perk gene was spec...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072952/ https://www.ncbi.nlm.nih.gov/pubmed/17727724 http://dx.doi.org/10.1186/1471-2121-8-38 |