Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer

BACKGROUND: Urodele amphibians like the axolotl are unique among vertebrates in their ability to regenerate and their resistance to develop cancers. It is unknown whether these traits are linked at the molecular level. RESULTS: Blocking p53 signaling in axolotls using the p53 inhibitor, pifithrin-α,...

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Detalles Bibliográficos
Autores principales: Villiard, Éric, Brinkmann, Henner, Moiseeva, Olga, Mallette, Frédérick A, Ferbeyre, Gerardo, Roy, Stéphane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072957/
https://www.ncbi.nlm.nih.gov/pubmed/17903248
http://dx.doi.org/10.1186/1471-2148-7-180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072957/
https://www.ncbi.nlm.nih.gov/pubmed/17903248
http://dx.doi.org/10.1186/1471-2148-7-180

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