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Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies

BACKGROUND: The recent development of new high-throughput technologies for SNP genotyping has opened the possibility of taking a genome-wide linkage approach to the search for new candidate genes involved in heredity diseases. The two major breast cancer susceptibility genes BRCA1 and BRCA2 are invo...

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Detalles Bibliográficos
Autores principales: Gonzalez-Neira, Anna, Rosa-Rosa, Juan Manuel, Osorio, Ana, Gonzalez, Emilio, Southey, Melissa, Sinilnikova, Olga, Lynch, Henry, Oldenburg, Rogier A, van Asperen, Christi J, Hoogerbrugge, Nicoline, Pita, Guillermo, Devilee, Peter, Goldgar, David, Benitez, Javier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072960/
https://www.ncbi.nlm.nih.gov/pubmed/17760956
http://dx.doi.org/10.1186/1471-2164-8-299