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Loss of antigen-presenting molecules (MHC class I and TAP-1) in lung cancer.

Presentation of endogenous antigenic peptides to cytotoxic T lymphocytes is mediated by the major histocompatibility complex (MHC) class I molecules. For the stable assembly of MHC class I complex it is necessary that the antigenic peptide is transported by the MHC-encoded transporters TAP-1 and TAP...

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Detalles Bibliográficos
Autores principales: Korkolopoulou, P., Kaklamanis, L., Pezzella, F., Harris, A. L., Gatter, K. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074307/
https://www.ncbi.nlm.nih.gov/pubmed/8546899