Preclinical in vivo efficacy of two 9-dihydrotaxane analogues against human and murine tumours.

Two 9-dihydrotaxane analogues were synthesised and tested for in vitro potency and in vivo efficacy against murine and human tumour xenografts in mice. The in vitro potency of 9-dihydrotaxol (9-DH-t) and 10-deacetyl-9-dihydrotaxol (10-DeAc-9-DH-t) was generally less than that of paclitaxel against h...

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Detalles Bibliográficos
Autores principales: Alder, J. D., Jarvis, K. P., Marsh, K. C., Klein, L. L., Clement, J. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074348/
https://www.ncbi.nlm.nih.gov/pubmed/8605087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074348/
https://www.ncbi.nlm.nih.gov/pubmed/8605087

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