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Preclinical in vivo efficacy of two 9-dihydrotaxane analogues against human and murine tumours.
Two 9-dihydrotaxane analogues were synthesised and tested for in vitro potency and in vivo efficacy against murine and human tumour xenografts in mice. The in vitro potency of 9-dihydrotaxol (9-DH-t) and 10-deacetyl-9-dihydrotaxol (10-DeAc-9-DH-t) was generally less than that of paclitaxel against h...
Autores principales: | Alder, J. D., Jarvis, K. P., Marsh, K. C., Klein, L. L., Clement, J. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074348/ https://www.ncbi.nlm.nih.gov/pubmed/8605087 |
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