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The role of apoptosis in bispecific antibody-mediated T-cell cytotoxicity.

In this report we describe the role of apoptosis in the process of tumour cell killing by bispecific monoclonal antibody (BsMAb)-redirected cytolytic T cells. The BsMAb used, BIS-1, has dual specificity for the CD3 complex on T cells and the pancarcinoma-associated 38 kDa transmembrane antigen EGP-2...

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Detalles Bibliográficos
Autores principales: Kroesen, B. J., Wellenberg, G. J., Bakker, A., Helfrich, W., The, T. H., de Leij, L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074386/
https://www.ncbi.nlm.nih.gov/pubmed/8611371