Comparison of monoclonal antibodies 17-1A and 323/A3: the influence of the affinity on tumour uptake and efficacy of radioimmunotherapy in human ovarian cancer xenografts.

The low-affinity monoclonal antibody (MAb) chimeric 17-1A(c-17-1A) and the high-affinity MAb mouse 323/A3 (m-323/A3) were used to study the effect of the MAb affinity on the tumour uptake and efficacy of radioimmunotherapy in nude mice bearing subcutaneously the human ovarian cancer xenografts FMa,...

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Detalles Bibliográficos
Autores principales: Kievit, E., Pinedo, H. M., Schlüper, H. M., Haisma, H. J., Boven, E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074456/
https://www.ncbi.nlm.nih.gov/pubmed/8595159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074456/
https://www.ncbi.nlm.nih.gov/pubmed/8595159

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