Cargando…
Comparison of monoclonal antibodies 17-1A and 323/A3: the influence of the affinity on tumour uptake and efficacy of radioimmunotherapy in human ovarian cancer xenografts.
The low-affinity monoclonal antibody (MAb) chimeric 17-1A(c-17-1A) and the high-affinity MAb mouse 323/A3 (m-323/A3) were used to study the effect of the MAb affinity on the tumour uptake and efficacy of radioimmunotherapy in nude mice bearing subcutaneously the human ovarian cancer xenografts FMa,...
Autores principales: | Kievit, E., Pinedo, H. M., Schlüper, H. M., Haisma, H. J., Boven, E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074456/ https://www.ncbi.nlm.nih.gov/pubmed/8595159 |
Ejemplares similares
-
Comparison of the pharmacokinetics, biodistribution and dosimetry of monoclonal antibodies OC125, OV-TL 3, and 139H2 as IgG and F(ab')2 fragments in experimental ovarian cancer.
por: Molthoff, C. F., et al.
Publicado: (1992) -
The efficacy of the anthracycline prodrug daunorubicin-GA3 in human ovarian cancer xenografts.
por: Houba, P. H., et al.
Publicado: (1998) -
The anti-tumour effects of the prodrugs N-l-leucyl-doxorubicin and vinblastine-isoleucinate in human ovarian cancer xenografts.
por: Boven, E., et al.
Publicado: (1992) -
Enhanced transplantability of human ovarian cancer lines in cyclophosphamide-pretreated nude mice.
por: Nauta, M. M., et al.
Publicado: (1986) -
Orthotopic xenografts of human melanoma and colonic and ovarian carcinoma in sheep to evaluate radioimmunotherapy.
por: Turner, J. H., et al.
Publicado: (1998)