Intracellular metabolism of the orally active platinum drug JM216: influence of glutathione levels.

JM216 (bis-acetato ammine dichloro cyclohexylamine Pt IV) is an oral platinum complex presently undergoing phase II clinical trials. Previous studies have identified some of its biotransformation products in clinical materials. This study evaluated the nature of JM216 biotransformation products intr...

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Detalles Bibliográficos
Autores principales: Raynaud, F. I., Odell, D. E., Kelland, L. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074629/
https://www.ncbi.nlm.nih.gov/pubmed/8695352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074629/
https://www.ncbi.nlm.nih.gov/pubmed/8695352

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