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No defect in G1/S cell cycle arrest in irradiated Li-Fraumeni lymphoblastoid cell lines.

The radiation response of Epstein-Barr virus (EBV)-immortalised lymphoblastoid cell lines derive from Li-Fraumeni syndrome (LFS) and LFS-like individuals was investigated. Cells from all LFS and LFS-like cases showed an accumulation of p53 protein following 137Cs gamma-irradiation, which was associa...

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Detalles Bibliográficos
Autores principales: Williams, K. J., Heighway, J., Birch, J. M., Norton, J. D., Scott, D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074690/
https://www.ncbi.nlm.nih.gov/pubmed/8795570