Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments.

The monoclonal anti-CEA antibody, A5B7, has previously been administered to patients for radioimmunotherapy (RIT). Long circulation time and the formation of an immune response have limited therapeutic success in the clinic. Antibody fragments can be used to reduce the in vivo circulation time, but...

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Detalles Bibliográficos
Autores principales: Casey, J. L., King, D. J., Chaplin, L. C., Haines, A. M., Pedley, R. B., Mountain, A., Yarranton, G. T., Begent, R. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074792/
https://www.ncbi.nlm.nih.gov/pubmed/8912535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074792/
https://www.ncbi.nlm.nih.gov/pubmed/8912535

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