HIV-1 Nef Employs Two Distinct Mechanisms to Modulate Lck Subcellular Localization and TCR Induced Actin Remodeling

The Nef protein acts as critical factor during HIV pathogenesis by increasing HIV replication in vivo via the modulation of host cell vesicle transport and signal transduction processes. Recent studies suggested that Nef alters formation and function of immunological synapses (IS), thereby modulatin...

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Detalles Bibliográficos
Autores principales: Haller, Claudia, Rauch, Susanne, Fackler, Oliver T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075162/
https://www.ncbi.nlm.nih.gov/pubmed/18030346
http://dx.doi.org/10.1371/journal.pone.0001212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075162/
https://www.ncbi.nlm.nih.gov/pubmed/18030346
http://dx.doi.org/10.1371/journal.pone.0001212

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