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Evidence of Compromised Blood-Spinal Cord Barrier in Early and Late Symptomatic SOD1 Mice Modeling ALS

BACKGROUND: The blood-brain barrier (BBB), blood-spinal cord barrier (BSCB), and blood-cerebrospinal fluid barrier (BCSFB) control cerebral/spinal cord homeostasis by selective transport of molecules and cells from the systemic compartment. In the spinal cord and brain of both ALS patients and anima...

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Detalles Bibliográficos
Autores principales: Garbuzova-Davis, Svitlana, Saporta, Samuel, Haller, Edward, Kolomey, Irina, Bennett, Steven P., Potter, Huntington, Sanberg, Paul R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075163/
https://www.ncbi.nlm.nih.gov/pubmed/18030339
http://dx.doi.org/10.1371/journal.pone.0001205