Cargando…
Evidence of Compromised Blood-Spinal Cord Barrier in Early and Late Symptomatic SOD1 Mice Modeling ALS
BACKGROUND: The blood-brain barrier (BBB), blood-spinal cord barrier (BSCB), and blood-cerebrospinal fluid barrier (BCSFB) control cerebral/spinal cord homeostasis by selective transport of molecules and cells from the systemic compartment. In the spinal cord and brain of both ALS patients and anima...
Autores principales: | Garbuzova-Davis, Svitlana, Saporta, Samuel, Haller, Edward, Kolomey, Irina, Bennett, Steven P., Potter, Huntington, Sanberg, Paul R. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075163/ https://www.ncbi.nlm.nih.gov/pubmed/18030339 http://dx.doi.org/10.1371/journal.pone.0001205 |
Ejemplares similares
-
Reduction of microhemorrhages in the spinal cord of symptomatic ALS mice after intravenous human bone marrow stem cell transplantation accompanies repair of the blood-spinal cord barrier
por: Eve, David J., et al.
Publicado: (2018) -
Blood-CNS Barrier Impairment in ALS patients versus an animal model
por: Garbuzova-Davis, Svitlana, et al.
Publicado: (2014) -
Endothelial and Astrocytic Support by Human Bone Marrow Stem Cell Grafts into Symptomatic ALS Mice towards Blood-Spinal Cord Barrier Repair
por: Garbuzova-Davis, Svitlana, et al.
Publicado: (2017) -
Plasma derived from human umbilical cord blood: Potential cell‐additive or cell‐substitute therapeutic for neurodegenerative diseases
por: Ehrhart, Jared, et al.
Publicado: (2018) -
Human Bone Marrow Endothelial Progenitor Cell Transplantation into Symptomatic ALS Mice Delays Disease Progression and Increases Motor Neuron Survival by Repairing Blood-Spinal Cord Barrier
por: Garbuzova-Davis, Svitlana, et al.
Publicado: (2019)