Cargando…

Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system

BACKGROUND: Matrix metalloproteinases (MMPs) are thought to mediate cellular infiltration in central nervous system (CNS) inflammation by cleaving extracellular matrix proteins associated with the blood-brain barrier. The family of MMPs includes 23 proteinases, including six membrane type-MMPs (MT-M...

Descripción completa

Detalles Bibliográficos
Autores principales: Toft-Hansen, Henrik, Babcock, Alicia A, Millward, Jason M, Owens, Trevor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075488/
https://www.ncbi.nlm.nih.gov/pubmed/17883829
http://dx.doi.org/10.1186/1742-2094-4-24