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Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system
BACKGROUND: Matrix metalloproteinases (MMPs) are thought to mediate cellular infiltration in central nervous system (CNS) inflammation by cleaving extracellular matrix proteins associated with the blood-brain barrier. The family of MMPs includes 23 proteinases, including six membrane type-MMPs (MT-M...
Autores principales: | Toft-Hansen, Henrik, Babcock, Alicia A, Millward, Jason M, Owens, Trevor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075488/ https://www.ncbi.nlm.nih.gov/pubmed/17883829 http://dx.doi.org/10.1186/1742-2094-4-24 |
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