Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon

BACKGROUND: Alpha interferon in combination with ribavirin is the standard therapy for hepatitis C virus infection. Unfortunately, a significant number of patients fail to eradicate their infection with this regimen. The mechanisms of IFN-resistance are unclear. The aim of this study was to determin...

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Detalles Bibliográficos
Autores principales: Hazari, Sidhartha, Taylor, Lizeth, Haque, Salima, Garry, Robert F, Florman, Sander, Luftig, Ronald, Regenstein, Frederic, Dash, Srikanta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075494/
https://www.ncbi.nlm.nih.gov/pubmed/17877826
http://dx.doi.org/10.1186/1743-422X-4-89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075494/
https://www.ncbi.nlm.nih.gov/pubmed/17877826
http://dx.doi.org/10.1186/1743-422X-4-89

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