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Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon

BACKGROUND: Alpha interferon in combination with ribavirin is the standard therapy for hepatitis C virus infection. Unfortunately, a significant number of patients fail to eradicate their infection with this regimen. The mechanisms of IFN-resistance are unclear. The aim of this study was to determin...

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Detalles Bibliográficos
Autores principales:	Hazari, Sidhartha, Taylor, Lizeth, Haque, Salima, Garry, Robert F, Florman, Sander, Luftig, Ronald, Regenstein, Frederic, Dash, Srikanta
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075494/ https://www.ncbi.nlm.nih.gov/pubmed/17877826 http://dx.doi.org/10.1186/1743-422X-4-89

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