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Inosine-Containing dsRNA Binds a Stress-Granule-like Complex and Downregulates Gene Expression In trans
Long double-stranded RNAs (dsRNAs) may undergo extensive modification (hyperediting) by adenosine deaminases that act on RNA (ADARs), where up to 50% of adenosine (A) residues are changed to inosine (I). Traditionally, consequences of A-to-I editing were thought to be limited to modified RNA itself....
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| Formato: | Texto |
| Lenguaje: | English |
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Cell Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075533/ https://www.ncbi.nlm.nih.gov/pubmed/17996712 http://dx.doi.org/10.1016/j.molcel.2007.09.005 |