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Transformation of cytogenetically normal chronic myelomonocytic leukaemia to an acute myeloid leukaemia and the emergence of a novel +13,+15 double trisomy resulting in an adverse outcome

A 58-year-old man was admitted with symptoms of lethargy and easy bruising for four months duration. Peripheral blood (PB) analysis revealed a white blood cell count (WBC) of 15.9 × 10(9)/l with monocytes 5.4 × 10(9)/l. Bone marrow (BM) was hypercellular with 15% blasts, monocytosis and trilineage d...

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Detalles Bibliográficos
Autores principales: McGrattan, Peter, Humphreys, Mervyn, Hull, Donald, McMullin, Mary F
Formato: Texto
Lenguaje:English
Publicado: The Ulster Medical Society 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075573/
https://www.ncbi.nlm.nih.gov/pubmed/17853637