An enhanced and sensitive autocrine stimulation by transforming growth factor-alpha is acquired in the brain metastatic variant of a human non-small-cell lung cancer cell line.

Transforming growth factor-alpha (TGF-alpha)-mediated autocrine regulation in human non-small-cell lung cancer (NSCLC) cells NCI-H226 and its brain metastatic variant H226Br were compared. An enhanced TGF-alpha-induced dose-dependent mitogenic responsiveness in H226Br cells was observed. Neutralisin...

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Detalles Bibliográficos
Autor principal: Fang, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077222/
https://www.ncbi.nlm.nih.gov/pubmed/8956792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077222/
https://www.ncbi.nlm.nih.gov/pubmed/8956792

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