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Targeting of stealth liposomes to erbB-2 (Her/2) receptor: in vitro and in vivo studies.

Long-circulating (stealth) liposomes coated with polyethylene glycol (PEG), which show reduced uptake by the reticuloendothelial system (RES) and enhanced accumulation in tumours, were used for conjugation to monoclonal antibodies (MAbs) as a drug-targeting device. A MAb (N-12A5) directed against er...

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Detalles Bibliográficos
Autores principales: Goren, D., Horowitz, A. T., Zalipsky, S., Woodle, M. C., Yarden, Y., Gabizon, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077226/
https://www.ncbi.nlm.nih.gov/pubmed/8956788