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Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1

Mrc1 (Mediator of Replication Checkpoint 1) is a component of the DNA replication fork machinery and is necessary for checkpoint activation after replication stress. In this study, we addressed the role of Mrc1 at uncapped telomeres. Our experiments show that Mrc1 contributes to the vitality of both...

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Detalles Bibliográficos
Autores principales: Tsolou, Avgi, Lydall, David
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077361/
https://www.ncbi.nlm.nih.gov/pubmed/17618841
http://dx.doi.org/10.1016/j.dnarep.2007.05.010