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The “Alternative” Choice of Constitutive Exons throughout Evolution

Alternative cassette exons are known to originate from two processes—exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution. We compiled a dataset of orthologous exons f...

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Detalles Bibliográficos
Autores principales: Lev-Maor, Galit, Goren, Amir, Sela, Noa, Kim, Eddo, Keren, Hadas, Doron-Faigenboim, Adi, Leibman-Barak, Shelly, Pupko, Tal, Ast, Gil
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077895/
https://www.ncbi.nlm.nih.gov/pubmed/18020709
http://dx.doi.org/10.1371/journal.pgen.0030203