Proteomic Shifts in Embryonic Stem Cells with Gene Dose Modifications Suggest the Presence of Balancer Proteins in Protein Regulatory Networks

Large numbers of protein expression changes are usually observed in mouse models for neurodegenerative diseases, even when only a single gene was mutated in each case. To study the effect of gene dose alterations on the cellular proteome, we carried out a proteomic investigation on murine embryonic...

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Detalles Bibliográficos
Autores principales: Mao, Lei, Zabel, Claus, Herrmann, Marion, Nolden, Tobias, Mertes, Florian, Magnol, Laetitia, Chabert, Caroline, Hartl, Daniela, Herault, Yann, Delabar, Jean Maurice, Manke, Thomas, Himmelbauer, Heinz, Klose, Joachim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077926/
https://www.ncbi.nlm.nih.gov/pubmed/18043732
http://dx.doi.org/10.1371/journal.pone.0001218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077926/
https://www.ncbi.nlm.nih.gov/pubmed/18043732
http://dx.doi.org/10.1371/journal.pone.0001218

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