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Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-κB in immortalized and malignant oral keratinocytes

BACKGROUND: Interleukin-8 (IL-8) is a cytokine that plays an important role in tumor progression in a variety of cancer types; however, its regulation is not well understood in oral cancer cells. In the present study, we examined the expression and mechanism of IL-8 in which it is involved by treati...

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Detalles Bibliográficos
Autores principales: Lee, Hwa-Jeong, Lee, Jun, Lee, Sun-Kyung, Lee, Suk-Keun, Kim, Eun-Cheol
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078595/
https://www.ncbi.nlm.nih.gov/pubmed/17850672
http://dx.doi.org/10.1186/1471-2407-7-176