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LPS induces IL-10 production by human alveolar macrophages via MAPKinases- and Sp1-dependent mechanisms
BACKGROUND: IL-10 is a cytokine mainly produced by macrophages that plays key roles in tolerance to inhaled antigens and in lung homeostasis. Its regulation in alveolar macrophages (HAM), the resident lung phagocytes, remains however unknown. METHODS: The present study investigated the role of intra...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080632/ https://www.ncbi.nlm.nih.gov/pubmed/17916230 http://dx.doi.org/10.1186/1465-9921-8-71 |