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Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg(2+)

BACKGROUND: The cell wall of Mycobacterium tuberculosis contains a wide range of phosphatidyl inositol-based glycolipids that play critical structural roles and, in part, govern pathogen-host interactions. Synthesis of phosphatidyl inositol is dependent on free myo-inositol, generated through dephos...

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Detalles Bibliográficos
Autores principales: Brown, Alistair K, Meng, Guoyu, Ghadbane, Hemza, Scott, David J, Dover, Lynn G, Nigou, Jérôme, Besra, Gurdyal S, Fütterer, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080633/
https://www.ncbi.nlm.nih.gov/pubmed/17725819
http://dx.doi.org/10.1186/1472-6807-7-55